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Auerovy tyčky; Schüffnerova tyčinka; Birbeckova granula; Apgar skóre; Bishopovo skóre; Aitkenova klasifikace; Angleova klasifikace; Blackova klasifikace; Breslowova klasifikace; Clarkova klasifikace; Fredricksonova klasifikace hyperlipoproteinemií; Childova klasifikace; Janského klasifikace; klasifikace defektů chrupu podle Kennedyho; klasifikace defektů chrupu podle Voldřicha; Landsteinerova klasifikace; Lennertova klasifikace; Lownova klasifikace; Lukesova-Collinsova klasifikace; Pauwelsova klasifikace; Klasifikace podle Potterové; Rappaportova klasifikace; Weberova klasifikace; šelest Austina Flinta; šelest Grahama Steela (Graham Steelův šelest); Rogerův šelest; Flintův šelest; Carey Coombsův šelest; Coombsův šelest; Cruveilhierův-Baumgartenův šelest; Babinského reflex; Bainbridgeův reflex; Bechtěrevův-Mendelův reflex; Bezoldův-Jarischův reflex; Eulerův-Liljestrandův reflex; Exnerův reflex; Gondův reflex; Gordonův reflex; Heringův reflex; Heringův-Breuerův reflex; Churchillův-Copeův reflex; Joffroyův reflex; Kehrerův reflex; Kischův reflex; Landauův reflex; Lériho reflex; Marinescuův-Radoviciho reflex; Mayerův reflex; Menelův-Bechtěrevův reflex; Monakovův reflex; Moroův reflex; Oppenheimův reflex; Puussepův reflex; Remakův reflex; Rossolimův reflex; Schaefferův reflex; Snellenův reflex; Trömnerův reflex; Vítkův reflex; Žukovského-Kornilův reflex;
List of eponymously named medical signs (en.wiki)[upravit | editovat zdroj]
Sign | Name | Specialty | Associated conditions | Descriptor |
---|---|---|---|---|
Aaron sign | Charles Dettie Aaron | surgery | appendicitis | epigastric pain with pressure on McBurney's point |
Abadie's sign | Jean Marie Charles Abadie | endocrinology | Graves' disease | levator palpebrae superioris spasm |
Abadie's symptom | Joseph Louis Irenée Jean Abadie | neurology | tabes dorsalis | absence of pain on Achilles tendon pressure |
Abderhalden reaction | Emil Abderhalden | obstetrics | pregnancy | serum reaction;obsolete |
Abelin reaction | Isaak Abelin | infectious disease | syphilis | presence of arsenical anti-syphilitic;obsolete |
Addis count | Thomas Addis | nephrology | pyelonephritis | quantitative cells and casts in 24hr. urine |
Adie pupil | William John Adie | neurology | ciliary nerve damage | dilated pupil, poorly reactive but with normal near accommodation |
Adson's sign | Alfred Washington Adson | vascular surgery | thoracic outlet syndrome | obliteration of radial pulse with manoeuvres |
Alexander's law | Gustav Alexander | neurology, neurosurgery, ENT | vestibular lesions | describes nystagmus in vestibular lesions |
Allen's test | Edgar Van Nuys Allen | vascular surgery, critical care[1] | arterial supply of the hand | tests for presence of palmar ulnar-radial anastomosis (palmar arch) |
Apgar score | Virginia Apgar | obstetrics | assess health of newborn | |
Apley grind test | Alan Graham Apley | orthopaedic surgery | meniscal lesions | manoeuvres to elicit knee pain |
Argyll Robertson pupils | Douglas Moray Cooper Lamb Argyll Robertson | neurology | neurosyphilis[2] | light-near dissociation |
Arneth count | Josef Arneth | haematology, nutrition | folate deficiency | lobulation of neutrophil nuclei |
Asboe-Hansen sign | Gustav Asboe-Hansen | dermatology | bullae | extension of a blister to adjacent unblistered skin when pressed |
Aschheim–Zondek test | Selmar Aschheim, Bernhard Zondek | obstetrics | normal pregnancy | oestral reaction in mouse injected with pregnant urine |
Aschoff body | Karl Albert Ludwig Aschoff | rheumatology, pathology | rheumatic fever | foci of interstitial inflammatiuon in the myocardium and elsewhere |
Ashby technique | Winifred Ashby | haematology, pathology | haemolysis | agglutination test for erythrocyte survival |
Auberger's blood group | Auberger (patient) | haematology | normal physiology | Aua antigen |
Auenbrugger's sign | Josef Leopold Auenbrugger | cardiology | pericardial effusion | bulging epigastrium |
Auer rods | John Auer | hematology | acute myeloid leukemia | cytoplasmic inclusions in myeloblasts |
Auspitz's sign | Heinrich Auspitz | dermatology | psoriasis | punctate bleeding when scales are scraped |
Austin Flint murmur | Austin Flint | cardiology | aortic insufficiency | mid-diastolic rumble heard at apex |
Babinski sign | Joseph Babinski | neurology | abnormal plantar reflex | dorsiflexion of the hallux with fanning of the remaining phalanges upon soft stimulation of the lateral plantar surface of the foot |
Bainbridge reflex | Francis Arthur Bainbridge | cardiology | normal physiology | increase in heart rate with increase in circulating blood volume |
Balbiani rings | Edouard-Gérard Balbiani | genetics | RNA transcription | large chromosome puff indicating site of RNA transcription |
Ballance's sign | Charles Alfred Ballance | general surgery | abdominal/splenic trauma | percussive dullness left flank, LUQ, percussive resonance right flank |
Bancroft's sign | Joseph Bancroft | vascular medicine | deep vein thrombosis | pain on anterior, but not lateral, compression of calf |
Bárány test | Robert Bárány | ENT,neurology | vertigo, vestibular dysfunction | nystagmus elicited by hot or cold irrigation of ear canal |
Barlow's maneuver | Thomas Geoffrey Barlow, English Pediatric Orthopedist, (1915–1975) | paediatrics, orthopaedic surgery | hip dysplasia | dislocation on adduction of hip |
Bart hemoglobin | Barts Hospital | Obstetrics, pathology | indicates a specific cause of death in some stillborns | Loss of all four alpha-globin genes (total alpha-thalassemia) leads to severely anemic stillborn babies with small amounts of an abnormal hemoglobin composed of four gamma sub-units (Bart's Hemoglobin) |
Bastian–Bruns sign | Henry Charlton Bastian, Ludwig Bruns | neurology | spinal cord transection | loss of muscle tone and reflexes below lesion level |
Battle's sign | William Henry Battle | neurosurgery/traumatology | basal skull fracture | mastoid ecchymosis |
Beau's lines | Joseph Honoré Simon Beau | dermatology, internal medicine | multiple, including trauma | transverse ridges on nails |
Beck's triad | Claude Schaeffer Beck | cardiology | cardiac tamponade | hypotension, increased central venous pressure (JVP), distant heart sounds |
Becker's sign | Otto Heinrich Enoch Becker | ophthalmology, endocrinology | thyrotoxicosis | visible pulsation of retinal arteries |
Beevor's sign | Charles Edward Beevor | neurology, neurosurgery | spinal trauma at T10, als,fsmd | caudal movement of navel on cervical flexion |
Bekhterev–Jacobsohn reflex | Vladimir Bekhterev, Louis Jacobsohn-Lask | neurology | pyramidal tract lesions | stroking dorsal radial skin, with forearm in supination, elicits wrist and finger flexion |
Bekhterev–Mendel reflex | Vladimir Bekhterev, Kurt Mendel | neurology | pyramidal tract lesions | toe flexion on percussion of dorsum of foot |
Bence Jones protein | Henry Bence Jones | hematology | multiple myeloma | |
Benedict solution | Stanley Rossiter Benedict | endocrinology | diabetes mellitus | reagent for presence of monosaccharides |
Berger wave (rhythm) | Hans Berger | neurology | normal physiology | electroencephalographic alpha wave |
Bezold–Jarisch reflex | Albert von Bezold, Adolf Jarisch | pharmacology, toxicology | effect of certain alkaloids | apnea, bradycardia, hypotension |
Bielschowsky's head tilt test | Alfred Bielschowsky | neurology, ophthalmology | lesions of cranial nerve IV | test for palsy of superior oblique muscle |
Bing's sign | Paul Robert Bing | neurology | pyramidal tract lesions | extension of the great toe on pricking the dorsum of the foot with a pin |
Biot's respiration | Camille Biot | neurology | brain stem herniation | quick shallow respirations followed by period of apnea |
Bitot's spots | Pierre Bitôt | ophthalmology | vitamin A deficiency | spots of keratin deposition in the conjunctiva |
Bjerrum scotoma | Jannik Peterson Bjerrum | ophthalmology | glaucoma | comet shaped visual field defect,extending temporally from the physiological blind spot |
Blumberg sign | Jacob Moritz Blumberg | surgery | peritonitis | rebound tenderness |
Boas' point | Ismar Isidor Boas | gastroenterology | gastric ulcer | dermal hyperaesthesia just left of T12 |
Boas' sign | Ismar Isidor Boas | gastroenterology | acute cholecystitis | dermal hyperaesthesia at inferior angle of R scapula |
Bodansky unit | Aaron Bodansky | clinical chemistry | unit of alkaline phosphatase concentration in blood | |
Boston's sign | Leonard N. Boston | ophthalmology, endocrinology | thyrotoxicosis | spasmodic ptosis on downward gaze |
Bouchard's nodes | Charles-Joseph Bouchard | rheumatology | osteoarthritis | bony outgrowths on dorsa of proximal interphalangeal joints |
Bracht–Wachter bodies | Erich Franz Eugen Bracht, Hermann Julius Gustav Wächter | cardiology | infective endocarditis | yellow-white spots in the myocardium |
Branham's sign | Henry Branham | pressing on proximal portion of AV fistula results in bradycardia | ||
Braxton Hicks contraction | John Braxton Hicks | obstetrics | normal pregnancy | "false labour". sporadic contractions beginning as early as mid 1st trimester |
Brewer infarcts | George Emerson Brewer | nephrology, pathology | pyelonephritis | dark red wedge shaped areas on kidney section resembling infarcts |
Brissaud's reflex | Édouard Brissaud | neurology | pyramidal tract lesions | plantar stimulation elicits contraction of tensor fasciae latae |
Broadbent inverted sign | Sir William Broadbent, 1st Baronet | cardiology | L atrial hypertrophy | systole palpable in posterior chest wall |
Broadbent sign | Walter Broadbent | cardiology | adhesive pericarditis | recession of L inferior intercostal spaces |
Broca aphasia | Paul Broca | neurology, neuropsychology | developmental or other pathology of various frontal cortical areas | expressive aphasia |
Brodie–Trendelenburg percussion test | Sir Benjamin Collins Brodie, 1st Baronet, Friedrich Trendelenburg | general medicine, surgery | varicose veins | superficial vein is percussed proximally; if impulse is felt over vein distally, valvular incompetence is present |
Brodie–Trendelenburg test | Sir Benjamin Collins Brodie, 1st Baronet, Friedrich Trendelenburg | general medicine,surgery | varicose veins | identifies level of valvular incompetence |
Brudziński neck sign | Józef Brudziński | neurology | meningitis | neck flexion elicits hip and knee flexion |
Brudziński cheek sign | Józef Brudziński | neurology | meningitis | pressure beneath zygoma elicits flexion of forearm |
Brudziński symphyseal sign | Józef Brudziński | neurology | meningitis | pressure over symphisis pubis elicits knee, hip flexion and leg abduction |
Brudziński reflex | Józef Brudziński | neurology | meningitis | passive flexion of knee to abdomen elicits flexion of contralateral hip and knee |
Bruit de Roger | Henri-Louis Roger | paediatric cardiology | ventricular septal defect | loud pansystolic murmur |
Bruns ataxia | Ludwig Bruns | neurology | frontal lobe lesions | difficulty moving feet in contact with floor, tendency to fall backwards |
Bruns nystagmus | Ludwig Bruns | neurology | cerebellopontine angle tumor, vestibular schwannoma | nystagmus that coarsens in amplitude on lateral gaze |
Brushfield spots | Thomas Brushfield | ophthalmology, genetics | Downs' syndrome or non-pathological | greyish-white spots at periphery of iris |
Burton line | Henry Burton | toxicology | lead poisoning | blue discolouration of the gingival border |
Cabot rings | Richard Cabot | hematology | lead poisoning, anaemias | threadlike strands in erythrocytes |
Caput medusae | Medusa | gastroenterology, surgery | portal hypertension | distended veins radiating from umbilicus |
Cardarelli's sign | Antonio Cardarelli | cardiology, thoracic surgery | aortic arch dilatation or aneurysm, mediastinal tumour | left displacement of trachea elicits palpable pulsation of same |
Carey Coombs murmur | Carey Coombs | cardiology,rheumatology | rheumatic fever | mid-diastolic rumble |
Carnett's sign | John Berton Carnett | primary care, surgery | abdominal mass and/or pain | supine patient lifts head from bed;↑ pain – abdominal wall ;↓ pain – intraperitoneal |
Carvallo's sign | José Manuel Rivero Carvallo | cardiology | tricuspid regurgitation | increase in volume of murmur on inspiration |
Casal collar | Gaspar Casal | nutrition | pellagra (niacin deficiency) | widely variable collar of dermatitis characteristically in c3,c4 dermatomes |
Casoni test | Tomaso Casoni | infectious disease, tropical medicine | hydatid disease | intradermal injection of hydatid fluid causing wheal |
Celsus signs of inflammation | Aulus Cornelius Celsus | various | inflammation | 1. Rubor (redness) 2. Tumor (swelling)3. Calor (heat) 4. Dolor (pain) |
Chaddock reflex | Charles Gilbert Chaddock | neurology | pyramidal lesions, corticospinal tract lesions | extension of big toe with stimulation of skin over lateral malleolus |
Chadwick sign | James Read Chadwick | obstetrics | pregnancy | cyanosis of vulva, vagina and cervix |
Charcot's triad | Jean-Martin Charcot | surgery | ascending cholangitis | jaundice, fever and chills, RUQ pain |
Charcot's triad | Jean-Martin Charcot | neurology | multiple sclerosis | nystagmus, intention tremor, staccato speech |
Charcot–Leyden crystals | Jean-Martin Charcot, Ernst Viktor von Leyden | pathology | any disorder characterized by eosinophil proliferation, e.g. ascariasis | lysophospholipase crystals in various tissues |
Cheyne–Stokes respiration | John Cheyne, William Stokes | palliative care | respiratory center damage | fluctuation between apnoea and tachypnoea |
Churchill–Cope reflex | Edward Delos Churchill, Oliver Cope | cardiology | heart failure | distension of pulmonary vascular bed causes tachypnoea |
Chvostek's sign | František Chvostek | endocrinology | hypocalcemia | tapping over facial nerve elicits abnormal muscle contraction(s) |
Claybrook sign | Edwin Claybrook | emergency medicine, surgery | blunt abdominal trauma | heart and/or breath sounds heard through abdominal wall indicate rupture of viscus |
Clutton's joints | Henry Hugh Clutton | paediatrics | congenital syphilis | painless symmetrical hydrarthroses, particularly of the knees |
Codman's triangle | Ernest Codman | oncology, orthopaedic surgery, radiology | osteosarcoma, Ewing's sarcoma | triangular subperiosteal growth |
Comby sign | Jules Comby | paediatrics | rubeola | whitish patches on gingiva and buccal mucosa |
Comolli's sign | Antonio Comolli | Orthopaedic surgery | Scapular fracture | triangular swelling corresponding to the outline of the scapula |
Coombs test | Robin Coombs | hematology | hemolytic anemia | |
Coons fluorescent antibody method | Albert Coons | immunology | detection of antibodies by fluorescence microscopy using fluorescein-labelled antibodies | |
Cornell's sign | ? | neurology | pyramidal tract lesions | scratching alongside big toe extensor tendon elicits an extensor plantar response |
Corrigan pulse | Dominic John Corrigan | cardiology | aortic insufficiency | carotid pulsations with abrupt ascending and descending phases |
Councilman body | William Thomas Councilman | infectious disease | yellow fever, viral haemorrhagic fevers | eosinophilic globules in liver |
Courvoisier's law | Ludwig Georg Courvoisier | gastroenterology | obstructive jaundice | palpable gall bladder w/ painless jaundice unlikely to be cholelithiasis |
Crichton-Browne sign | Sir James Crichton-Browne | neuropsychiatry | 'general paresis' | tremor at corners of mouth and of outer canthus |
Crowe sign | Frank W. Crowe | dermatology | neurofibromatosis type I | axillary freckling |
Cruveilhier–Baumgarten bruit | Jean Cruveilhier, Paul Clemens von Baumgarten | hepatology | Cruveilhier–Baumgarten disease | bruit around the umbilicus |
Cullen's sign | Thomas S. Cullen | surgery | intraabdominal haemorrhage | ecchymosis around umbilicus predicts onset of acute pancreatitis |
Curschmann spirals | Heinrich Curschmann | pulmonology | asthma | spiral mucus plugs found in sputum |
Cushing's triad | Harvey Cushing | neurology | raised intracranial pressure | elevated systolic bp, bradycardia, irregular respiration |
Dagher Maneuver | Nabil Dagher | trauma surgery | penetrating pelvic trauma | bimanual palpation of foreign object lodged in pelvis with one digit in an incision lateral to the anus and the other digit inserted in the rectum |
Dahlén–Fuchs nodules | Johan Dahlén, Ernst Fuchs | ophthalmology | sympathetic ophthalmia | |
Dahl's sign | K.V. Dahl | pulmonology | COPD | pigmented calluses on anterior surface of thighs (from leaning on elbows) |
Dalrymple sign | John Dalrymple | ophthalmology, endocrinology | thyrotoxicosis | widened palpebral opening |
Dance's sign | Jean Baptiste Hippolyte Dance | (paediatric)surgery | ileo-cecal intussusception | empty RLQ (retracted right iliac fossa) |
Darier's sign | Ferdinand-Jean Darier | allergy,dermatology | urticaria pigmentosa | dermatographia |
Dawson's fingers | James Walker Dawson | neurology | multiple sclerosis | characteristic fingerlike appearance of lateral ventricle on mri, ct, or at autopsy |
De Musset's sign | Alfred de Musset | cardiology | aortic insufficiency | head nodding in time with heartbeat |
Dennie–Morgan fold | "Charles Clayton Dennie | |||
DB Morgan" | dermatology | atopic dermatitis | accentuated fold below the lower eyelid | |
Destot's sign | Etienne Destot | orthopaedic surgery | pelvic fracture | ecchymosis superior to inguinal ligament, in scrotum or of thigh |
Dix–Hallpike test | Margaret R. Dix, Charles Skinner Hallpike | Otolaryngology | Benign paroxysmal positional vertigo | Elicitation of extreme vertigo upon lateral movement of a patient's head when lying in a supine position |
Döhle bodies | Karl Gottfried Paul Döhle | pathology | various including trauma and neoplasm | basophilic inclusions in peripheral cytoplasm of neutrophils |
Doi's sign | Hitoka Doi | neurology | Eaton–Lambert syndrome | reappearance of absent deep tendon reflexes after short period of maximal muscle contraction |
Dunphy sign | Osborne Joby Dunphy | surgery | appendicitis | increase in abdominal pain on coughing |
Duroziez's sign | Paul Louis Duroziez | cardiology | aortic insufficiency | double bruit heard over femoral artery when it is compressed distally (see Traube's sign) |
Elschnig spots | Anton Elschnig | ophthalmology | hypertensive retinopathy | |
Epstein's pearls | Alois Epstein | paediatrics | normal newborn | cystic papules on palate |
Ewart's sign | William Ewart | cardiology | pericardial effusion | percussive dullness, aegophony and bronchial breath sounds at L scapular tip |
Faget sign | Jean-Charles Faget | infectious disease | Yellow fever Typhoid Fever tularaemia brucellosis others | the unusual constellation of fever and bradycardia |
Finkelstein's test | Harry Finkelstein | rheumatology | DeQuervain's tenosynovitis | |
Forchheimer spots | Frederick Forchheimer | paediatrics | rubella | small red spots on the soft palate |
Fothergill's sign | John Fothergill | surgery | rectus sheath hematoma | anterior abdominal mass which does not cross the midline and is still palpable when abdominal wall muscles are tensed |
Fox's sign | George Henry Fox | gastroenterology | haemorrhagic pancreatitis | ecchymosis of inguinal ligament (blood tracks retroperitoneally) |
Frank's sign | Sanders T. Frank | cardiology | ischaemic heart disease | ear crease indicating risk of heart disease (disputed) |
Friedreich's sign | Nikolaus Friedreich | cardiology | constrictive pericarditis, tricuspid insufficiency | collapse of distended neck veins in diastole |
Froment's sign | Jules Froment | neurology | ulnar nerve palsy | patient required to hold paper between thumb and palm (against attempt to withdraw);ability to do so is assessed |
Gallavardin phenomenon | Louis Gallavardin | cardiology | aortic stenosis | dissociation of musical and noisy elements in ejection murmur |
Gamna–Favre bodies | "Carlos Gamna, | |||
Maurice Favre" | histology | lymphogranuloma venereum | basophilic cytoplasmic inclusion bodies | |
Gandy–Gamna nodules | "Charles Gandy, | |||
Carlos Gamna" | histology | splenomegaly due to portal hypertension and sickle cell disease | small yellow-brown foci in the spleen | |
Garrod's pads | Archibald Garrod | dermatology | repeated extreme tension of extensor tendon in interphalangeal joint | thickening of skin and tissue over interphalangeal joint |
Gerhardt's sign | Carl Jakob Adolf Christian Gerhardt | controversial: see references | ||
Glasgow Coma Scale | Glasgow | neurology | A neurological scale which aims to give a reliable and objective way of recording the conscious state of a person for initial as well as subsequent assessment. | The sum of Eye, Motor and Verbal responses. |
Goetz sign | Robert H. Goetz | Patent Ductus Arteriosus | Seen during right ventriculography in the setting of a patent ductus arteriosus, the Goetz sign refers to the negative contrast effect seen in the pulmonary artery from non-contrast enhanced blood shunting left to right from the aorta | |
Gonda's sign | Viktor Gonda, Ukrainian Neuropsychiatrist, (1889-1959) | neurology | pyramidal tract lesions | flexing then suddenly releasing the 4th toe elicits an extensor plantar response |
Goodell's sign | William Goodell | obstetrics | pregnancy | softening of the vaginal part of the cervix during the first trimester |
Goodsall's rule | David Henry Goodsall | gastroenterology, general surgery | anal fistula | anatomical relationships, differentiation of fistula types |
Gordon's sign | Alfred Gordon | neurology | pyramidal tract lesions | squeezing the calf muscle elicits an extensor plantar response |
Gottron's papules | Heinrich Adolf Gottron | rheumatology | dermatomyositis | Scaling, erythematous eruption or dusky red patches over the knuckles, elbows and knees |
Gowers' sign[3] | William Richard Gowers | neurology | muscular dystrophy | |
Graham Steell murmur | Graham Steell | cardiology | mitral stenosis | pulmonary regurgitation murmur in patients with pulmonary hypertension secondary to mitral stenosis |
Grey Turner's sign | George Grey Turner | surgery | retroperitoneal hemorrhage | flank ecchymosis |
Griffith's sign | ? | endocrinology | Graves' ophthalmopathy | lid lag of the lower eyelid on upward eye movement |
Gunn's sign | Robert Marcus Gunn | ophthalmology | hypertension | AV "nicking" or "nipping" in hypertensive retinopathy |
Hamman's sign | Louis Hamman | thoracic surgery | oesophageal perforation w/ pneumomediastinum | crepitus in sync w/ heartbeat but not respiration |
Hampton's hump | Aubrey Otis Hampton | pulmonology, radiology | pulmonary embolus with infarct | wedge shaped consolidation at periphery with base on the pleura |
Hampton's line | Aubrey Otis Hampton | radiology, gastroenterology | peptic ulcer | line on barium meal indicating mucosal oedema associated with ulcer |
Hannington-Kiff sign | John G. Hannington-Kiff | general surgery | obturator hernia | absent thigh adductor reflex with positive patellar reflex |
Harrison's groove | Edward Harrison | internal medicine | rickets | rib deformity at the lower thorax |
Hatchcock's sign | ? | paediatrics, infectious disease | mumps | tenderness behind angle of jaw (typically before swelling is evident) |
Heberden's node | William Heberden | rheumatology | osteoarthritis | same as bouchard's nodes, but over dip joints |
Hegar's sign | Ernst Ludwig Alfred Hegar | obstetrics | normal pregnancy | softening of cervical isthmus appearin between 4th and 6th weeks (usually) |
Hess test | Alfred Fabian Hess | internal medicine | capillary fragility | appearance of petechiae after compression of arm by bandage or blood pressure cuff |
Hildreth's sign | DH Hildreth | dermatology | glomus tumor | Relief of pain at tumor site upon vascular occlusion of limb, with acute return of pain on reperfusion |
Hippocratic face | Hippocrates | palliative care | impending death | |
Hippocratic fingers | Hippocrates | pulmonary medicine | chronic hypoxia | clubbing of distal phalanges |
Hirschberg test | Julius Hirschberg | ophthalmology | strabismus | corneal reflection centred (-) or not centred (+) on pupil |
Hoffmann's sign | Johann Hoffmann | neurology | corticospinal tract lesions | tapping distal phalanx of 3rd or 4th finger elicits flexion of same in thumb |
Hollenhorst plaque | Robert Hollenhorst | ophthalmology | hypertension, coronary artery disease, and/or diabetes | cholesterol embolus(i) of retinal artery(ies) |
Homans' sign | John Homans | thrombosis | deep venous thrombosis | knee bent, ankle abruptly dorsiflexed, popliteal pain |
Hoover's sign (leg paresis) | Charles Franklin Hoover | neurology, psychiatry | lower extremity paresis | differentiates organic from non-organic etiology |
Hoover's sign (pulmonary) | Charles Franklin Hoover | pulmonology | COPD | inward movement of lower ribs during inspiration |
Howship–Romberg sign | "John Howship, | |||
Moritz Heinrich Romberg" | surgery | obturator hernia | pain from an obturator hernia radiating to knee | |
Hubscher's Maneuver | Podiatry | Flexible vs rigid flatfoot deformity | Patient bears weight on foot. Hallux is dorsiflexed. If arch is recreated, test is positive. Indicative of flexible deformity | |
Hutchinson's freckle | Sir Jonathan Hutchinson | dermatology | melanoma | precancerous facial pigmentation |
Hutchinson's pupil | Sir Jonathan Hutchinson | neurology | oculomotor nerve lesion | dilated pupil on the side of an intracranial lesion due to IIIrd nerve compression |
Hutchinson's sign | Sir Jonathan Hutchinson | ophthalmology | herpes zoster | lesion on tip of the nose which can presage ocular herpes zoster |
Hutchinson's teeth[4] | Sir Jonathan Hutchinson | pediatrics | congenital syphilis | small, widely spaced incisors with notched biting surfaces |
Hutchinson's triad | Sir Jonathan Hutchinson | pediatrics | congenital syphilis | interstitial keratitis,nerve deafness, Hutchinson's teeth |
Janeway lesion | Theodore Caldwell Janeway | cardiology | infective endocarditis | palmar or plantar erythematous or haemorrhagic papules |
Jendrassik maneuver | Ernő Jendrassik | neurology | hyporeflexia | compares patellar reflex w/ and w/o distraction |
Jobe's relocation test | Christopher Jobe | orthopedics | ||
Joffroy's sign | Alexis Joffroy | endocrinology | exophthalmos in Graves disease | lack of forehead wrinkling when patient looks up with head bowed |
Jolly's test | Friedrich Jolly | neurology | myasthenia gravis or Eaton–Lambert syndrome | electromyography test using repeated stimuli to show fatiguability in myasthenia |
Jones criteria | T. Duckett Jones | rheumatology | rheumatic fever | criteria used to diagnose rheumatic fever |
Kanavel's sign | Allen B. Kanavel | orthopedics, rheumatology | tenosynovitis of flexor digitorum tendon | (1) finger held in slight flexion, (2) fusiform swelling, (3) tenderness along the flexor tendon sheath, and (4) pain with passive extension of the digit. |
Kayser–Fleischer ring | "Bernhard Kayser, | |||
Bruno Fleischer" | neurology,gastroenterology | Wilson's disease(hepatolenticular degeneration) | ring of brownish copper deposit at corneo-scleral junction | |
Kehr's sign | Hans Kehr | trauma surgery | ruptured spleen | referred pain to L shoulder |
Kelly's sign | Howard Atwood Kelly | surgery | visible response of ureter when touched (means of identifying same) | |
Kerley lines | Peter Kerley | radiology | pulmonary edema | |
Kernig's sign | Woldemar Kernig | neurology | meningism, meningitis, subarachnoid haemorrhage | hip and knee fully flexed, extension of knee elicits pain and/or opisthotonus |
Koebner's phenomenon | Heinrich Koebner | dermatology | various conditions | |
Koeppe's nodules | Leonhard Koeppe | ophthalmology | uveitis | granulomatous nodules at pupillary margin |
Koplik's spots | Henry Koplik | pediatrics | measles | |
Korotkoff sounds | Nikolai Korotkov | cardiology | auscultatory sphygmomanometry | Korotkov described 5 sounds. Only the first (the onset of audible sound,and corresponding to systolic pressure) and the fifth (sound becomes inaudible,corresponding to diastolic pressure) are of practical clinical significance (however,see:Auscultatory gap) |
Kussmaul breathing[5] | Adolph Kussmaul | endocrinology | metabolic acidosis | laboured deep breathing with normal or reduced frequency |
Kussmaul's sign | Adolph Kussmaul | cardiology | various, including right side failure | increased jugular distension on inspiration |
Kveim test | Morten Ansgar Kveim | pulmonary medicine | sarcoidosis | intradermal injection of lymphatic extract from known sufferer; obsolete |
Lachman maneuver | John Lachman | orthopedic surgery | anterior cruciate ligament injury | modified anterior drawer test with knee in less flexion |
Ladin's sign | Louis Julius Ladin, Lithuanian-American Gynecologist, (1862-1951) | obstetrics | normal pregnancy | softening of uterus; similar to Hegar's sign |
Lancisi's sign | Giovanni Maria Lancisi | cardiology | tricuspid regurgitation | giant v-wave in seen in jugular vein |
Larrey's sign | Dominique Larrey | rheumatology | sacroiliitis | pain in sacroiliac area on sitting down on hard chair |
Lasègue's sign | Charles Lasègue | neurosurgery, orthpaedic surgery | lumbar disc lesions, sciatica | better known as straight leg raise test |
Leopold's maneuver | Christian Gerhard Leopold | obstetrics | determination of fetal lie | |
Leser–Trélat sign | "Edmund Leser, | |||
Ulysse Trélat" | oncology | malignant neoplasm | sudden onset of multiple pruritic seborrheic keratoses | |
Levine's sign | Samuel A. Levine | cardiology | myocardial infarction | patient clenches fist over chest when asked to describe pain |
Lhermitte's sign | Jean Lhermitte | neurology | lesions of cervical cord dorsal columns or caudal medulla, MS, chemotherapy, Behçet's disease | electrical sensation down the back and into limbs with neck flexion or extension |
Liebermeister's rule | Carl von Liebermeister | internal medicine | For each fever degree Celsius an increase of 8 beats per minute in cardiac frequency | |
Lisch nodule | Karl Lisch | ophthalmology | type I neurofibromatosis | yellow brown hamartomata on iris |
Lisker's sign | ? | internal medicine | deep venous thrombosis | tenderness on percussion of antero-medial tibia |
Litten's sign | Moritz Litten | cardiology | infective endocarditis | cotton-wool exudate in the retina |
Lombard effect | Étienne Lombard | psychiatry | malingering due to simulated deafness | automatic rise in the loudness of a person's voice when they speak in noise |
Louvel's sign | ? | internal medicine | deep venous thrombosis | increased pain along vein with valsalva; proximal pressure prevents this |
Lowenberg's sign | ? | vascular medicine | deep vein thrombosis | immediate pain on inflating blood pressure cuff around calf |
MacDonald triad | John M. MacDonald | psychiatry | sociopathic personality disorder | eneuresis, firesetting and animal torture predictive of future criminal behaviour |
Macewen's sign | Sir William Macewen | neurology, neurosurgery | hydrocephalus, brain abscess | resonance on percussion of fronto-temporo-parietal suture |
Magnan's sign | Valentin Magnan | addiction medicine | cocaine dependence | feeling of moving foreign body under the skin |
Mantoux test | Charles Mantoux | infectious disease | tuberculosis | intradermal protein derivative – diameter of wheal evaluated |
Marcus Gunn pupil | Robert Marcus Gunn | ophthalmology, neurology | severe retinal disease, lesion of optic nerve anterior to chiasm | Relative pupil dilatation when light swings to the affected side |
Markle sign | ? | surgery | appendicitis | RLQ pain on dropping from standing on toes to heels |
Mayne's sign | ? | cardiology | aortic insufficiency | diastolic blood pressure drop of >15mmHg on raising arm |
McBurney's point | Charles McBurney | surgery | appendicitis | 2/3 of the way lateral on a line from umbilicus to anterior superior iliac spine (corresponds to junction of vermiform appendix and cecum) |
McConnell's sign | M.V. McConnell | cardiology | pulmonary embolism | echocardiography finding of akinesia of the mid-free wall of the right ventricle but normal motion of the apex |
McMurray test | Thomas Porter McMurray | orthopaedics | meniscal tear | knee extended, valgus stress applied, leg rotated produces palpable or audible click |
Means–Lerman scratch | J. Lerman, J.H. Means | endocrinology | hyperthyroidism | systolic heart murmur similar to pericardial rub |
Mees' lines | R.A. Mees | toxicology | arsenic or heavy metal poisoning | transverse white lines across the nails |
Mellignhoff's sign | Mellinghoff | hyperbaric medicine | cutaneous decompression sickness | coughing or Valsalve accentuates the venous markings of an erysipeloid rash |
Mentzer index | William C. Mentzer Jr. | hematology | microcytic anemia | differentiates iron deficiency anaemia from beta thalassaemia |
Miller Fisher test | C. Miller Fisher | neurology | normal pressure hydrocephalus | Improvement in cognitive function after withdrawal of CSF during lumbar puncture used to confirm diagnosis |
Moniz sign | António Egas Moniz | neurology | pyramidal tract lesions | forceful plantar flexion of the ankle elicits an extensor plantar response |
Möbius sign | Paul Julius Möbius | endocrinology | thyrotoxicosis | inability to maintain convergence of eyes |
Muehrcke's lines | Robert C. Muehrcke | nephrology, oncology | hypoalbuminaemia, chemotherapy | paired transverse white lines on nail bed |
Mulder's sign | Jacob D. Mulder | neurology, podiatry | Morton's neuroma | transverse compression of the forefoot elicits pain in the distribution of the affected nerve |
Müller's maneuver | Johannes Peter Müller | pulmonology | collapsed section of airway | patient attempts to breathe in with nose and mouth closed (opposite of Valsalva maneuver) |
Müller's sign | Friedrich von Müller | cardiology | aortic insufficiency | visible pulsation or bobbing of uvula |
Murphy's punch sign | John B. Murphy | urology | perinephric abscess | punch tenderness at the costovertebral angle |
Murphy's sign | John B. Murphy | surgery | cholecystitis | hesitation on inspiration while gall bladder is palpated |
Myerson's sign | Abraham Myerson | neurology | Parkinson's disease | inability to resist blinking when glabella is percussed |
Naegele's rule | Franz Karl Naegele | gynecology | gestation | method of estimating due date |
Nardi test | George Nardi | gastroenterology | dysfunction of sphincter of Oddi | administration of morphine and neostigmine reproduces sharp LUQ pain; not in general use |
Nikolsky's sign | Pyotr Nikolsky | dermatology | various, including pemphigus vulgaris | mild shear stress applied to skin causes bullae to form |
O'Brien's test | ? | |||
O'Donoghue's triad | D. O'Donoghue | orthopaedics, sports medicine | knee injury | coincidence of anterior cruciate injury,medial collateral injury and meniscal tear |
Oliver's sign | William Silver Oliver | cardiology | aortic arch aneurysm | caudal movement of trachea with systole |
Oppenheim's sign | Hermann Oppenheim | neurology | pyramidal tract lesions | irritation downward of the medial tibia causes dorsiflexion of big toe |
Ortolani test | Marino Ortolani | pediatrics & orthopedics | congenital hip dislocation | palpable clunk on moving hip |
Osborn wave | John J. Osborn (1917–) | cardiology, emergency medicine | hypothermia | positive deflection at QRS-ST junction |
Osler's node | Sir William Osler | internal medicine | various, including SBE and SLE | painful red lesions on the pads of the fingers and plantar surfaces |
Osler's sign | Sir William Osler | internal medicine | atherosclerosis | falsely elevated bp reading due to incompressibility of calcified vessels |
Palla's sign | ? | internal medicine | pulmonary embolism | enlarged right descending pulmonary artery on chest x-ray |
Pastia's sign | Constantin Chessec Pastia | pediatrics | scarlet fever | lines of confluent petechiae in skin creases (associated with Scarlatiniform rash and strep pyogenes) |
Patrick's test | Hugh Talbot Patrick | rheumatology | sacroiliitis | external rotation of the hip causes pain |
Peabody's sign | C.N. Peabody | internal medicine | deep vein thrombosis | calf muscle spasm when raising the affected leg with the foot extended |
Pemberton's sign | Hugh Pemberton | thoracic surgery | retrosternal mass with superior vena cava syndrome | arms elevated over head elicits facial plethora, distended neck veins and inspiratory stridor |
Phalen's maneuver | George S. Phalen | rheumatology, hand surgery | carpal tunnel syndrome | 30–60 seconds of full forced flexion of wrist elicits symptoms |
Piskaçek's sign | Ludwig Piskaçek | obstetrics | normal pregnancy | palpable lateral bulge at tubal-uterine junction; present at 7–8 weeks |
Plummer's nail | Henry Stanley Plummer | endocrinology | thyrotoxicosis | onycholysis especially of ring and little fingers |
Pratt's sign | Gerald H. Pratt | internal medicine | deep venous thrombosis | pain elicited by compression of posterior calf |
Queckenstedt's maneuver | Hans Heinrich Georg Queckenstedt | neurology | spinal stenosis | bilateral jugular vein pressure during lumbar puncture causes sudden rise in CSF pressure |
Quincke's sign | Heinrich Irenaeus Quincke | cardiology | aortic insufficiency | visible pulsation in ungual capillary bed |
Reynolds' pentad | B.M. Reynolds | gastroenterology | ascending cholangitis | Charcot's triad + hypotension and altered mental state |
Riesman's sign | David Riesman | endocrinology | thyrotoxicosis | bruit over globe of the eye |
Rigler's sign[6] | Leo George Rigler | radiology, abdominal surgery | pneumoperitoneum | gas outlines both mucosal and serosal surfaces of bowel |
Rinne test | Heinrich Adolf Rinne | ENT, neurology, audiometry | hearing impairment | comparison of air conduction to bone conduction differentiates sensorineural from conductive deafness |
Romaña's sign | Cecilio Romaña | tropical medicine | Chagas' disease | painless unilateral periorbital swelling |
Romberg test | Moritz Heinrich Romberg | neurology | dorsal column lesions, cerebllar lesions, alcohol intoxication | inability to maintain posture with eyes closed |
Rose's sign | ? | vascular medicine | deep vein thrombosis | Warm, stiff feeling of skin when affected leg is pinched |
Rosenbach's test | Ottomar Rosenbach | clinical chemistry | bilirubinuria | colour produced on addition of nitric acid |
Rossolimo's sign | Grigory Ivanovich Rossolimo | neurology | pyramidal tract lesions | percussion of the tips of the toes causes exaggerated flexion of the toes |
Roth's spots | Moritz Roth | ophthalmology, internal medicine | various, including SBE and systemic vasculitides | retinal haemorrhages with pale centres seen at fundoscopy |
Rovsing's sign | Niels Thorkild Rovsing | general surgery | appendicitis | palpation of LLQ elicits pain in RLQ |
Rumpel–Leede sign | "Theodor Rumpel, | |||
Carl Stockbridge Leede" | haematology | capillary fragility | petechiae seen after compression by tourniquet | |
Russell's sign | Gerald Russell | psychiatry | bulimia nervosa | scarring of the dorsum of one hand (contact with incisors when purging) |
Salus's sign | Robert Salus | ophthalmology | hypertension | deflection of retinal veins at right angle junctions due to elongation or shortening of connected arterioles |
Schaeffer's sign | Max Schaeffer | neurology | pyramidal tract lesions | squeezing the Achilles tendon elicits an extensor plantar response |
Schamroth's window test | Leo Schamroth | pulmonology, cardiology | chronic hypoxia | identifies clubbing of distal phalanges |
Schiller's test | Walter Schiller | gynecology | cervical cancer | affected areas of cervix fail to stain brown with iodine solution |
Schilling test | Robert F. Schilling | internal medicine | pernicious anaemia, coeliac disease, other malabsorption disorders | B12 radioassay; rare |
Schirmer's test | Otto Schirmer | ophthalmology | keratoconjunctivitis sicca, as in Sjögren's syndrome | quantifies lacrimal secretion |
Schober test | Paul Schober | physiatry, rheumatology, orthopaedics | various disorders of lumbar vertebrae | quantifies lumbar flexion |
Sherren's triangle | James Sherren | surgery | appendicitis | area of hyperaesthesia over the right lower abdomen |
Shone's complex | John D. Shone | cardiology | congenital heart defect | supravalvular mitral ring, parachute deformity of mitral valve, subaortic stenosis and coarctation of the aorta |
Siegrist streaks | August Siegrist | ophthalmology | malignant hypertension | hyperpigmented sreaks parallel to choroidal vessels |
Simmonds' test | Franklin Adin Simmonds | orthopaedics | Achilles tendon rupture | squeezing of calf fails to produce plantar flexion |
Sims–Huhner test | Harry M. Sims, Max Huhner | reproductive medicine | infertility | determination of sperm count and motility in a sample taken from the cervical canal within an hour of intercourse |
Sister Mary Joseph nodule[7] | Sister Mary Joseph Dempsey (born Julia Dempsey) | oncology | various abdominal malignancies | palpable lymph node in the umbilicus |
Spurling's test | Roy Glenwood Spurling | neurology | cervical radiculopathy | axial compression and rotation of cervical spine to the side of symptoms causes pain |
Stellwag's sign | Karl Stellwag von Carion | endocrinology | thyrotoxicosis | infrequent and/or incomplete blinking, accompanied by Dalrymple's sign |
Still's murmur | Sir George Frederick Still | paediatric cardiology | subaortic stenosis, small Ventricular septal defect | systolic ejection sound ; vibratory/musical; best heard at left lower sternal border |
Stransky's sign | ? | neurology | pyramidal tract lesions | sudden abduction and release of little toe causes extensor plantar response |
Stroop test | John Ridley Stroop | neuropsychology | various, including ADHD and schizophrenia | reaction times for incongruent stimuli (e.g., word red printed in blue) |
Strümpell's sign | Adolph Strümpell | neurology | spastic pareses of the lower extremity | failure of abrupt passive flexion of the hip and/or knee to elicit dorsiflexion and adduction of foot |
Terry's nails | R. Terry | internal medicine | various including hepatic failure | white 'ground glass' nails;absence of lunula |
Terry-Thomas sign | Terry-Thomas | Orthopaedics | Scapho-lunate dissociation | Gap between the scaphoid and lunate bones on AP wrist radiograph |
Thomas test | Hugh Owen Thomas | Orthopaedics | Fixed flexion deformity of hip | Supine patient flexes one hip whilst keeping other leg flat; back arches if flexion deformity is present |
Throckmorton's reflex | Tom Bentley Throckmorton | neurology | pyramidal tract lesions | pressure over dorsal big toe MTP joint elicits an extensor plantar response |
Tinel's sign | Jules Tinel | neurology | neuritis, compression disorders | 'DTP' – distal tingling on percussion |
Todd's paresis | Robert Bentley Todd | neurology | seizure disorders | focal weakness for as much as 48 hours after seizure |
Traube's sign | Ludwig Traube | various | splenomegaly | dull percussion sound over Traube's space |
Trendelenburg's sign | Friedrich Trendelenburg | neurology | inferior gluteal palsy, other causes of hip abductors weakness | pelvic tilt contralateral to 'stance leg' |
Troisier's sign | Charles Emile Troisier | internal medicine, oncology | Various abdominal malignancies, especially stomach cancer | Enlargement of the left supraclavicular lymph node (=Virchow's node) |
Trousseau's sign of malignancy | Armand Trousseau | internal medicine | various malignancies, including pancreatic | spontaneous thrombosis of multiple veins, including portal circulation |
Trousseau's sign of latent tetany | Armand Trousseau | internal medicine, endocrinology | hypocalcaemia | in hypocalcaemia, occlusion of brachial artery induces carpal spasm |
Uhthoff's phenomenon | Wilhelm Uhthoff | neurology | multiple sclerosis | ↑ in neurological symptoms with exercise or other increase in body temperature |
Unterberger test | Siegfried Unterberger | neurology, ENT | vestibular lesions | patient walks in place with eyes closed;direction of rotation indicates vestibular lesion on that side |
Virchow's node | Rudolf Virchow | internal medicine, oncology | Various abdominal malignancies, especially stomach cancer | Enlargement of the left supraclavicular lymph node (=Troisier's sign) |
Virchow's triad | Rudolf Virchow | hematology | etiology of thrombosis | Hypercoagulability, Hemodynamic changes (stasis, turbulence) and Endothelial injury/dysfunction |
Von Braun-Fernwald's sign | Karl von Braun-Fernwald | obstetrics | pregnancy | softening of the uterine fundus at the site of implantation at 4–5 weeks gestation |
Von Graefe sign | Albrecht von Graefe | endocrinology | Graves' disease | ' lid lag'; immobility of upper lid on downward gaze |
Wada test | Juhn Atsushi Wada | neurology | epilepsy, anatomical lesions of cerebrum | short acting barbiturate injected in internal carotid; lateralizes language function |
Waddell's signs | G. Waddell | primary care, psychiatry | chronic pain | identify non-organic sources of low back pain |
Waddell's triad | J.P. Waddell | paediatric trauma | child pedestrian stuck by motor vehicle | Head trauma, thoracic and/or abdominal trauma, femoral fracture |
Watson's water hammer pulse | Thomas Watson | cardiology | aortic regurgitation | bounding forceful pulse elicited with postural manoeuvres |
Wellens' sign or warning | Hein Wellens | cardiology | severe stenosis of LAD | characteristic ekg changes |
Westermark sign | ? | pulmonology | pulmonary embolism | Area of oligaemia on chest x-ray |
Whipple's triad | Allen Whipple | endocrinology | hypoglycemia | 1.symptoms associated with hypoglycaemia 2. measured low serum glucose 3. relief of symptoms with administration of glucose p.o. or iv |
Wickham's striae | Louis Frédéric Wickham | dermatology | lichen planus | white or greyish lines on the lichen planus lesions |
Widal test | Georges-Fernand Widal | microbiology | enteric fever | serum agglutination; obsolete(?) |
Winterbottom's sign | Thomas Masterman Winterbottom | tropical medicine | trypanosomiasis | posterior cervical chain adenopathy |
Wolff–Parkinson–White triad | "Sir John Parkinson, | |||
Paul Dudley White, | ||||
Louis Wolff" | cardiology | supraventricular tachycardia | pre-excitation on ECG | |
Wright's maneuver | ? | |||
Yeoman's test | ? | rheumatology | sacroiliitis | sacroiliac pain on rotation of ilium and extension of hip |
Yergason's test | ? | orthopedic surgery | bicipital tendinitis | anterior shoulder pain with resisted supination of the forearm |